NeuroMatrix is an extracellular matrix produced in vitro by primary human astrocytes. This product is composed of proteins secreted and assembled by astrocytes during cell culture. In vivo, astrocytes are the most abundant glial cell type and are essential for neuron survival. This astrocyte-derived extracellular matrix provides support for a variety of iPSC-derived and primary neural cell types in mono and co-culture, including cortical neurons, cortical astrocytes, microglia, spinal motor neurons, and neural stem cells. It can be used for a variety of applications, including excitotoxicity studies and neurite outgrowth.