Achieve maturation of human iPSC-derived cardiomyocytes in 7 days

 
Within 7 days of seeding on CELLvo™ Matrix Plus, human iPSC-derived cardiomyocytes developed a rod-shaped morphology and became binucleated.

Within 7 days of seeding on CELLvo™ Matrix Plus, human iPSC-derived cardiomyocytes developed a rod-shaped morphology and became binucleated.

 

CELLvo™ Matrix Plus promotes rapid maturation of commercially available hiPSC-CMs in 2D monolayer formats supporting high throughput preclinical drug toxicity screening assays.

The human cell-derived extracellular matrix creates a biologically relevant microenvironment that provides all the cues cells expect to receive within the cell culture dish.

CELLvo™ Matrix Plus is a ready-to-use substrate that is available on a variety of standard cell culture surfaces. Contact StemBioSys to find out how other specialized plates can be customized to support your experimental design.

 
 

Matrigel

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CELLvo™ Matrix Plus

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Shown above is a comparison of human iPSC-derived cardiomyocytes cultured on Matrigel versus CELLvo™ Matrix Plus after 7 days. Cells seeded on CELLvo™ Matrix Plus display a rod-shape morphology with organization of sarcomeres parallel to the long axis of the cardiomyocyte and are binucleated.

CELLvo™ Matrix Plus is available for your research studies now. Choose from a variety of cell culture surface formats, or inquire about our custom coating service.